LONDON, May 12:
Being a current smoker or having chronic obstructive pulmonary disease (COPD) are associated with an increased risk of severe complications and higher death risk from COVID-19 infection, according to a study.
COPD is a common, persistent dysfunction of the lung associated with a limitation in airflow.
The researchers from the University College London in the UK noted that an estimated 251 million people worldwide are affected by COPD. Given the effects of the SARS-CoV-2 coronavirus on respiratory function, they sought to understand the prevalence and the effects of COPD in COVID-19 patients.
The study, published in the journal PLOS ONE, systematically searched databases of scientific literature to find existing publications on the epidemiological, clinical characteristics and features of COVID-19, and the prevalence of COPD in COVID-19 patients.
As many as 123 potentially relevant papers were narrowed to 15 that met all quality and inclusion guidelines, the researchers said. The included studies had a total of 2,473 confirmed COVID-19 patients, they said.
The study found that critically ill COVID-19 patients with COPD had a 63 per cent risk of severe disease and a 60 per cent risk of mortality.
On the other hand, critically ill patients without COPD had only a 33.4 per cent risk of severe disease, and 55 per cent risk of mortality, the researchers said. (PTI)