Excelsior Correspondent
JAMMU, Oct 10: In a major achievement, a scientist of SKUAST-Jammu has isolated anti-cancer active compound from the fruit part of Kamala Tree.
While working on Jammu botanicals, SKUAST Scientist Dr Vikas Sharma, son of Harbans Lal Sharma and Pushplata Sharma, of Channi Himmat, yielded this very significant consensus from medicinal view point as he isolated an active ingredient from the fruit part Mallotus philippinensis, popularly known as “Kamala tree or sindur”, that possesses significant in vitro cytotoxic potential against eight human cancer cells from six different tissues.
The active ingredient has the potential to serve as a candidate drug for cancer therapy and may very well be exploited for cancer treatment to provide a great promise and service to cancer patients. The anticancer molecule can be modified through chemical means into a new drug for the management of neuroblastoma, ovarian and colon carcinomas as it observed to be most cytotoxic against these human cancer cells with 99-100% activity. The advance research in this regard is going on in the Division of Biochemistry, Faculty of Basic Sciences, SKUAST-Jammu in collaboration with Cancer Pharmacology Division, Indian Institute of Integrative Medicine (IIIM-CSIR), Jammu for further mechanistic evaluation.
Mallotus philippinensis was collected from Nandni Hills of Jammu district and evaluated / tested for its in vitro cytotoxic effect against various human cancer cells.
Dr. Vikas Sharma is presently posted as Assistant Professor (Biochemistry), Faculty of Basic Sciences, SKUAST-Jammu, Main Campus Chatha and has been working on anticancer potential of local medicinal plants.
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